The Efficacy of Spinal Manipulation, Amitriptyline and the Combination of Both Therapies for the Prophylaxis of Migraine Headache
The Efficacy of Spinal Manipulation, Amitriptyline and the Combination of Both Therapies for the Prophylaxis of Migraine Headache
SOURCE: J Manipulative Physiol Ther 1998 (Oct); 21 (8): 511–519
Nelson CF, Bronfort G, Evans R, Boline P,
Goldsmith C, Anderson AV
Center for Clinical Studies,
Northwestern College of Chiropractic,
Bloomington, MN 55431, USA.
BACKGROUND: Migraine headache affects approximately 11 million adults in the United States. Spinal manipulation is a common alternative therapy for headaches, but its efficacy compared with standard medical therapies is unknown.
OBJECTIVE: To measure the relative efficacy of amitriptyline, spinal manipulation and the combination of both therapies for the prophylaxis of migraine headache.
DESIGN: A prospective, randomized, parallel-group comparison. After a 4-wk baseline period, patients were randomly assigned to 8 wk of treatment, after which there was a 4-wk follow-up period.
SETTING: Chiropractic college outpatient clinic.
PARTICIPANTS: A total of 218 patients with the diagnosis of migraine headache.
INTERVENTIONS: An 8-wk course of therapy with spinal manipulation, amitriptyline or a combination of the two treatments.
MAIN OUTCOME MEASURES: A headache index score derived from a daily headache pain diary during the last 4 wk of treatment and during the 4-wk follow-up period.
There are more articles like this @ our: