Physiological Responses Induced by Manual Therapy in Animal Models: A Scoping Review
Physiological Responses Induced by Manual Therapy in Animal Models: A Scoping Review
SOURCE: Frontiers in Neuroscience 2020 (May 8); 14: 430
| OPEN ACCESS |
Carla Rigo Lima, Daniel Fernandes Martins and William Ray Reed
Rehabilitation Science Program,
University of Alabama at Birmingham,
Birmingham, AL, United States
Background: Physiological responses related to manual therapy (MT) treatment have been investigated over decades using various animal models. However, these studies have not been compiled and their collective findings appraised. The purpose of this scoping review was to assess current scientific knowledge on the physiological responses related to MT and/or simulated MT procedures in animal models so as to act as a resource to better inform future mechanistic and clinical research incorporating these therapeutic interventions
Methods: PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Cochrane, Embase, and Index of Chiropractic Literature (ICL) were searched from database inception to August 2019. Eligible studies were:
(b) non-cadaveric animal-based;
(c) original data studies;
(d) included a form of MT or simulated MT as treatment;
(e) included quantification of at least one delivery parameter of MT treatment;
(f) quantification of at least one physiological measure that could potentially contribute to therapeutic mechanisms of action of the MT.
MT studies were categorized according to three main intervention types:
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