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Frank M. Painter

About Frank M. Painter

I was introduced to Chiro.Org in early 1996, where my friend Joe Garolis helped me learn HTML, the "mark-up language" for websites. We have been fortunate that journals like JMPT have given us permission to reproduce some early important articles in Full-Text format. Maintaining the Org website has been, and remains, my favorite hobby.

The Global Burden of Neck Pain

By |November 22, 2018|Neck Pain|

The Global Burden of Neck Pain: Estimates From the Global Burden of Disease 2010 Study

The Chiro.Org Blog


SOURCE:   Ann Rheum Dis. 2014 (Jul); 73 (7): 1309–1315

Damian Hoy, Lyn March, Anthony Woolf, Fiona Blyth, Peter Brooks, Emma Smith, Theo Vos, Jan Barendregt, Jed Blore, Chris Murray, Roy Burstein, Rachelle Buchbinder

University of Queensland,
Herston, Queensland, Australia.


OBJECTIVE:   To estimate the global burden of neck pain.

METHODS:   Neck pain was defined as pain in the neck with or without pain referred into one or both upper limbs that lasts for at least 1 day. Systematic reviews were performed of the prevalence, incidence, remission, duration and mortality risk of neck pain. Four levels of severity were identified for neck pain with and without arm pain, each with their own disability weights. A Bayesian meta-regression method was used to pool prevalence and derive missing age/sex/region/year values. The disability weights were applied to prevalence values to derive the overall disability of neck pain expressed as years lived with disability (YLDs). YLDs have the same value as disability-adjusted life years as there is no evidence of mortality associated with neck pain.

RESULTS:   The global point prevalence of neck pain was 4.9% (95% CI 4.6 to 5.3). Disability-adjusted life years increased from 23.9 million (95% CI 16.5 to 33.1) in 1990 to 33.6 million (95% CI 23.5 to 46.5) in 2010. Out of all 291 conditions studied in the Global Burden of Disease 2010 Study, neck pain ranked 4th highest in terms of disability as measured by YLDs, and 21st in terms of overall burden.

There are more articles like this @ our new:

Global Burden of Disease Page

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The Global Burden of Low Back Pain

By |November 20, 2018|Low Back Pain|

The Global Burden of Low Back Pain: Estimates from the Global Burden of Disease 2010 study

The Chiro.Org Blog


SOURCE:   Ann Rheum Dis. 2014 (Jun); 73 (6): 968–974

Prof Theo Vos, PhD, Abraham D Flaxman, PhD, Mohsen Naghavi, PhD, Prof Rafael Lozano, MD, Catherine Michaud, MD, Prof Majid Ezzati et. al.

School of Population Health,
Brisbane, QLD, Australia


OBJECTIVE:   To estimate the global burden of low back pain (LBP).

METHODS:   LBP was defined as pain in the area on the posterior aspect of the body from the lower margin of the twelfth ribs to the lower glutaeal folds with or without pain referred into one or both lower limbs that lasts for at least one day. Systematic reviews were performed of the prevalence, incidence, remission, duration, and mortality risk of LBP. Four levels of severity were identified for LBP with and without leg pain, each with their own disability weights. The disability weights were applied to prevalence values to derive the overall disability of LBP expressed as years lived with disability (YLDs). As there is no mortality from LBP, YLDs are the same as disability-adjusted life years (DALYs).

RESULTS:   Out of all 291 conditions studied in the Global Burden of Disease 2010 Study, LBP ranked highest in terms of disability (YLDs), and sixth in terms of overall burden (DALYs). The global point prevalence of LBP was 9.4% (95% CI 9.0 to 9.8). DALYs increased from 58.2 million (M) (95% CI 39.9M to 78.1M) in 1990 to 83.0M (95% CI 56.6M to 111.9M) in 2010. Prevalence and burden increased with age.

You may also want to check out:

Years Lived with Disability (YLDs) for 1160 Sequelae of 289 Diseases and Injuries 1990-2010

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Cost-effectiveness of Spinal Manipulation, Exercise

By |November 15, 2018|Cost-Effectiveness|

Cost-effectiveness of Spinal Manipulation, Exercise, and Self-management for Spinal Pain Using an Individual Participant Data Meta-analysis Approach: A Study Protocol

The Chiro.Org Blog


SOURCE:   Chiropractic & Manual Therapies 2018 (Nov 13); 26: 46

Brent Leininger, Gert Bronfort, Roni Evans, James Hodges, Karen Kuntz and John A. Nyman

Integrative Health & Wellbeing Research Program,
Earl E. Bakken Center for Spirituality & Healing,
University of Minnesota,
420 Delaware St SE,
Minneapolis, MN 55455, USA


Background   Spinal pain is a common and disabling condition with considerable socioeconomic burden. Spine pain management in the United States has gathered increased scrutiny amidst concerns of overutilization of costly and potentially harmful interventions and diagnostic tests. Conservative interventions such as spinal manipulation, exercise and self-management may provide value for the care of spinal pain, but little is known regarding the cost-effectiveness of these interventions in the U.S. Our primary objective for this project is to estimate the incremental cost-effectiveness of spinal manipulation, exercise therapy, and self-management for spinal pain using an individual patient data meta-analysis approach.

Methods/design   We will estimate the incremental cost-effectiveness of spinal manipulation, exercise therapy, and self-management using cost and clinical outcome data collected in eight randomized clinical trials performed in the U.S. Cost-effectiveness will be assessed from both societal and healthcare perspectives using QALYs, pain intensity, and disability as effectiveness measures. The eight randomized clinical trials used similar methods and included different combinations of spinal manipulation, exercise therapy, or self-management for spinal pain. They also collected similar clinical outcome, healthcare utilization, and work productivity data. A two-stage approach to individual patient data meta-analysis will be conducted.

There are more articles like this @ our:

The Cost-Effectiveness of Chiropractic Page and the:

Chiropractic and Spinal Pain Management Page and the:

Exercise and Chiropractic Care Page

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The Role of Vitamin D in the Pathogenesis

By |November 12, 2018|Scoliosis, Vitamin D|

The Role of Vitamin D in the Pathogenesis of Adolescent Idiopathic Scoliosis

The Chiro.Org Blog


SOURCE:   Asian Spine J. 2018 (Oct 16) [Epub]

Shu-Yan Ng, Josette Bettany-Saltikov, Irene Yuen Kwan Cheung, Karen Kar Yin Chan

Institute of Health and Social Care,
Teesside University,
Middlesbrough, UK.


Several theories have been proposed to explain the etiology of adolescent idiopathic scoliosis (AIS) until present. However, limited data are available regarding the impact of vitamin D insufficiency or deficiency on scoliosis. Previous studies have shown that vitamin D deficiency and insufficiency are prevalent in adolescents, including AIS patients. A series of studies conducted in Hong Kong have shown that as many as 30% of these patients have osteopenia. The 25-hydroxyvitamin D3 level has been found to positively correlate with bone mineral density (BMD) in healthy adolescents and negatively with Cobb angle in AIS patients; therefore, vitamin D deficiency is believed to play a role in AIS pathogenesis. This study attempts to review the relevant literature on AIS etiology to examine the association of vitamin D and various current theories. Our review suggested that vitamin D deficiency is associated with several current etiological theories of AIS. We postulate that vitamin D deficiency and/or insufficiency affects AIS development by its effect on the regulation of fibrosis, postural control, and BMD. Subclinical deficiency of vitamin K2, a fat-soluble vitamin, is also prevalent in adolescents; therefore, it is possible that the high prevalence of vitamin D deficiency is related to decreased fat intake. Further studies are required to elucidate the possible role of vitamin D in the pathogenesis and clinical management of AIS.

There are more articles like this @ our:

Nutrition Section
and the:

Scoliosis and Chiropractic Page

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Low Back Pain: The Potential Contribution of Supraspinal

By |November 8, 2018|Low Back Pain|

Low Back Pain: The Potential Contribution of Supraspinal Motor Control and Proprioception

The Chiro.Org Blog


SOURCE:   Neuroscientist. 2018 (Nov 2) [Epub]

Michael Lukas Meier, Andrea Vrana1, and Petra Schweinhardt

Integrative Spinal Research,
Department of Chiropractic Medicine,
University Hospital Balgrist,
Zurich, Switzerland.


Motor control, which relies on constant communication between motor and sensory systems, is crucial for spine posture, stability and movement. Adaptions of motor control occur in low back pain (LBP) while different motor adaption strategies exist across individuals, probably to reduce LBP and risk of injury. However, in some individuals with LBP, adapted motor control strategies might have long-term consequences, such as increased spinal loading that has been linked with degeneration of intervertebral discs and other tissues, potentially maintaining recurrent or chronic LBP. Factors contributing to motor control adaptations in LBP have been extensively studied on the motor output side, but less attention has been paid to changes in sensory input, specifically proprioception.

Furthermore, motor cortex reorganization has been linked with chronic and recurrent LBP, but underlying factors are poorly understood. Here, we review current research on behavioral and neural effects of motor control adaptions in LBP. We conclude that back pain-induced disrupted or reduced proprioceptive signaling likely plays a pivotal role in driving long-term changes in the top-down control of the motor system via motor and sensory cortical reorganization. In the outlook of this review, we explore whether motor control adaptations are also important for other (musculoskeletal) pain conditions.

There are more articles like this @ our:

Low Back Pain and Chiropractic Page

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