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A randomized double-blind placebo-controlled study adding high dose vitamin D to analgesic regimens in patients with musculoskeletal pain

By |April 14, 2015|Vitamin D|

Source Pub Med pubmed/25801891

Lupus. 2015 Apr;24(4-5):483-9. doi: 10.1177/0961203314558676.
Gendelman O, Itzhaki D, Makarov S, Bennun M, Amital H.

Abstract

BACKGROUND:

The current mode of therapy for many patients with musculoskeletal pain is unsatisfactory.

PURPOSE:

We aimed to assess the impact of adding 4000 IU of vitamin D on pain and serological parameters in patients with musculoskeletal pain.

MATERIALS AND METHODS:

This was a randomized, double-blinded and placebo-controlled study assessing the effect of 4000 IU of orally given vitamin D3 (cholecalciferol) (four gel capsules of 1000 IU, (SupHerb, Israel) vs. placebo on different parameters of pain. Eighty patients were enrolled and therapy was given for 3 months. Parameters were scored at three time points: prior to intervention, at week 6 and week 12. Visual analogue scale (VAS) scores of pain perception were recorded following 6 and 12 weeks. We also measured serum levels of leukotriene B4 (LTB4), interleukin 6 (IL-6), tumor necrosis factor alpha (TNFα) and prostaglandin E2 (PGE2) by ELISA.

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ACA House of Delegates Passes 2 Controversial Resolutions

By |April 14, 2015|Expanded Practice|

ACA House of Delegates Passes 2 Controversial Resolutions

The Chiro.Org Blog


SOURCE:   Dynamic Chiropractic – April 15, 2015


The American Chiropractic Association’s House of Delegates voted on 30 resolutions at its annual business meeting in Washington D.C., but two in particular took immediate center stage due to their controversial nature.

The first is “Resolution #2 – The Six Key Elements of a Modern Chiropractic Act.” Resolution #2 includes two “elements” that call for “prescriptive authority.” The second, “Resolution #12 – Establishment of College of Pharmacology & Toxicology” establishes the “College of Chiropractic Pharmacology and Toxicology of the American Chiropractic Association.”

To better understand how these resolutions are viewed by ACA delegates – and perhaps the profession at large – we asked Michael Taylor, DC (Oklahoma delegate) and Edward McKenzie, DC (Kansas delegate) to give their opinions regarding the resolutions. (Dr. Taylor, an author on both resolutions, deferred to Tony Hamm, DC, newly re-elected ACA president, who is also an author on Resolution #12.)

Dynamic Chiropractic:   The Six Key Elements of a Modern Chiropractic Act (Resolution #2) includes the following four elements:

1)   “Chiropractic Physician” and “Chiropractic Medicine” as the Regulatory Terms of Licensure;

2)   Scope of Practice Determined by Doctoral and Post-Doctoral Education, Training and Experience Obtained Through Appropriately Accredited Institutions;

3)   Full Management, Referral and Prescription Authority for Patient Examination, Diagnosis, Differential Diagnosis and Health Assessment; and

4)   Full Management, Referral and Prescription Authority for the Care and Treatment of Neuromusculoskeletal and Other Health Conditions or Issues.

In your opinion, do these four elements suggest doctors of chiropractic should have the authority to prescribe drugs?

Dr. Hamm:   No. The American Chiropractic Association supports the Summit statement: “The drug issue is a non-issue because no chiropractic organization in the Summit promotes the inclusion of prescription drug rights and all chiropractic organizations in the Summit support the drug-free approach to health care.”

Dr. McKenzie:   There is a saying in the Midwest: “If it looks like a pig, acts like a pig and smells like a pig … it probably is a pig … and no matter how much lipstick you put on it … it is still a pig.”

In my opinion, it would be hard to draw any other conclusion than to suggest that these elements are there explicitly for the purpose of furthering the agenda towards acquiring prescription authority.

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Infant Probiotic Exposure Dramatically Reduces ADHD or Aspergers

By |April 8, 2015|Asperger Syndrome, Attention Deficit|

A Possible Link Between Early Probiotic Intervention and the Risk of Neuropsychiatric Disorders Later in Childhood: A Randomized Trial

The Chiro.Org Blog


SOURCE:   Pediatr Res. 2015 (Jun); 77 (6): 823–828


Pärtty A, Kalliomäki M, Wacklin P, Salminen S, Isolauri E

Department of Pediatrics,
University of Turku and Turku University Hospital,
Turku, Finland

Finnish Red Cross Blood Service,
Helsinki, Finland.

Functional Foods Forum,
University of Turku,
Turku, Finland.


BACKGROUND:   Recent experimental evidence suggests that gut microbiota may alter function within the nervous system providing new insight on the mechanism of neuropsychiatric disorders.

METHODS:   Seventy-five infants who were randomized to receive Lactobacillus rhamnosus GG (ATCC 53103) or placebo during the first 6 mo of life were followed-up for 13 y. Gut microbiota was assessed at the age of 3 wk, 3, 6, 12, 18, 24 mo, and 13 y using fluorescein in situ hybridization (FISH) and qPCR, and indirectly by determining the blood group secretor type at the age of 13 y. The diagnoses of attention deficit hyperactivity disorder (ADHD) and Asperger syndrome (AS) by a child neurologist or psychiatrist were based on ICD-10 diagnostic criteria.

There are other articles like this @ our:

Acidophilus and Pre/Probiotics Page

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A Randomized Controlled Trial on Treatment of Cervicogenic Sudden Hearing Loss With Chiropractic

By |April 1, 2015|Hearing Loss|

A Randomized Controlled Trial on Treatment of Cervicogenic Sudden Hearing Loss With Chiropractic

The Chiro.Org Blog


SOURCE:   Zhongguo Gu Shang. 2015 (Jan);   28 (1):   62–65


Zhou X, Luo HS, He JY, Wang R, Zhuang Y, Zhan Q.


OBJECTIVE:   To investigate the clinical effect and safety of chiropractic in treating cervicogenic sudden hearing loss.

METHODS:   From January 2011 to October 2013, 90 patients with cervicogenic sudden hearing loss were randomly divided into treatment group and control group according to the random number table produced by SPSS 19.0 software. In the treatment group, there were 17 males and 28 females, aged from 31 to 62 years old with an average of (47.57±9.43) years; course of disease was from 1 to 3 days with an average of (1.43±0.68) days; pure-tone audiometry score was from 46.5 to 77.8 dB with the mean of (61.20±9.83) dB; Northwick Park Neck Pain Questionnaire (NPQ) score was from 17 to 31 scores with an average of (23.46±7.18) scores. In the control group, there were 15 males and 30 females, aged from 28 to 64 years old with an average of (45.77±6.99) years; course of disease was from 1 to 3 days with an average of (1.50±0.73) days; pure-tone audiometry score was from 48.1 to 75.0 dB with the mean of (63.91±8.05) dB; Northwick Park Neck Pain Questionnaire (NPQ) score was from 20 to 29 scores with an average of (25.61±10.43) scores. The patients of control group were treated with dexamethasone intravenous drip of 10 mg, 3 days later, decreased to 5 mg, 3 days again. And with the methycobal intravenous drip of 500 μg, treatment continued for 10 days. The patients of treatment group were treated with chiropractic additionally except for the therapeutic methods of control group. Chiropractic included local muscle loosening, attacking point, bilateral pulling atlanto-axial joint, and continuous treatment for 10 days. The pure-tone audiometry score and NPQ score were compared between two groups after treatment.

There are more articles like this @ our:

Deafness and Chiropractic Page

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Cross-Sectional Analysis of Telomere Length in People 33-80 Years of Age: Effects of Dietary Supplementation

By |March 28, 2015|Supplementation|

Cross-Sectional Analysis of Telomere Length in People 33-80 Years of Age: Effects of Dietary Supplementation

The Chiro.Org Blog


SOURCE:   Poster Presentation at the American College of Nutrition’s 55th Annual Conference


Calvin B. Harley, PhD; Joanne Chan, BS;
Marsha Blauwkamp, PhD; Francis C. Lau, PhD, FACN;
Jamie F. McManus, MD, FAAFP; Drew Watson, PhD;
Evangelos Hytopoulos, PhD; and
Bruce P. Daggy, PhD, FACN

Telomere Diagnostics,
Menlo Park, CA


Abstract

Telomere length has been associated with aging, age-related diseases, adverse conditions, and mortality. Moreover, studies in humans suggest a causal role of short telomeres or accelerated telomere shortening in disease and mortality risk. A previous cross-sectional study has shown that Shaklee supplement usage significantly improved various health parameters and nutritional status. [1] The objective of the current cross-sectional study was to explore the effect of dietary supplementation on telomere length.

The normal range of telomere lengths was determined from saliva samples in a population of healthy, non-smoking subjects aged 33-80 from the San Francisco Bay Area (control group; n=324; 147 males and 177 females) who took no more than 3 supplements daily. The telomere lengths of heavy supplement users (supplement group; n=80; 21 males and 59 females), the majority of whom took more than 12 Shaklee supplements at least 4 days per week, were compared to the age-matched control group. Disease and smoking status were not exclusion criteria for the supplement group. Telomere length was measured by quantitative PCR to determine the telomere-to-single copy gene (T/S) ratio. Change in T/S ratio over time was fitted to a linear regression. Blood biomarkers were also assessed.

Overall, women had longer telomeres than men in the control group, but this trend was reversed in the supplement group. (Refer to Figures 3 & 4 below) T/S ratio of the supplement group was 11.2% greater than that of the control group (p<0.0001). Supplementation resulted in a greater treatment effect in men vs. women (p<0.005). By linear regression, the rate of change in T/S ratio was reduced by 40% in the supplement group vs control. Blood biomarkers in both groups were comparable and were within the normal physiological ranges.

There are more articles like this @ our:

All About Telomeres Page

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